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Director: Brahm Goldstein MD, FAAP, FCCM
Specialty: Pediatrics
Sub-Specialty: Pediatric Critical Care
Organization: Doernbecher Children's Hospital, Oregon Health & Science University
Address: 3181 SW Sam Jackson Park Road
Mail Code DC10S
Portland, OR 97201
Phone: 503-418-5177
Fax: 503-418-5199
Email: goldsteb@ohsu.edu
Medical School: SUNY Health Sciences Center at Syracuse, NY
Residency 1: UCLA- Pediatrics
Residency 2: n/a
Addtn’l Training: Boston Children’s Hospital, Peds Cardiology (1 year); Massachusetts General Hospital, Peds Critical Care (1year)
Practice Philosophy: I am the Director of Medical Services for Doernbecher Children’s Hospital and a non-practicing member of the Division of Pediatric Critical Care participating in PICU research projects.
Professional Biosketch: 1986-1989 InstructorHarvard Medical School

1989-1994 Assistant ProfessorUniversity of Rochester School of Medicine & Dentistry

1994-2000 Associate ProfessorOregon Health Sciences University

2000-present ProfessorOregon Health Sciences University
Computer/Telemedicine/ Informatics Projects: Our research program involves the application of computerized linear and nonlinear time series analysis methods to study clinical and experimental models of critical illness and injury. Through complex computer analysis of the ECG, arterial pressure waveform, and other analog physiologic signals, we use time and frequency domain measurements of heart rate variability (e.g. power spectral analysis) and newer, nonlinear measurements (e.g. fractal landscape analysis, approximate entropy, correlation dimension) to measure cardiovascular control mechanisms and organ system interactions in disease states such as acute brain injury, sepsis and septic shock, hemorrhagic shock, toxemia of pregnancy, and other clinical and laboratory models.

These methods have provided new insights into the pathophysiology involved in autonomic control of the cardiovascular system in critically ill and injured patients. We also collaborate with a number of investigators from around the country to evaluate and develop new methods for nonlinear analysis.
We believe that computerized nonlinear analysis of the ECG and other cardiovascular signals may eventually enable physicians to detect changes in beat-to-beat variability of heart rate or rhythm, blood pressure, vascular resistance, or stroke volume on a real-time basis. This may provide information about cardiovasculature regulatory mechanisms that will signal impending cardiovascular collapse, hypotension, dysrhythmias, or cardiac arrest and thus allow for early intervention and improved outcome.


Website Address: http://www.ohsudoernbecher.com
Languages: English, Spanish